CU-CPD107

CAT: 0931-T35349-01Size: 1 mgDry Ice: NoHazardous: No
CAT#: T35349-01Size: 1 mg
Selected
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2573912-32-8
Target
TLR
Related Pathways
Immunology/Inflammation
Purity
0.9886
Bioactivity
CU-CPD107 is a selective agonist of toll-like receptor 8 (TLR8) and also shows activation activity against ssRNA ligands. CU-CPD107 acts as an inhibitor of TLR8 signaling in the presence of R848 (IC50=13.7 ?M) . CU-CPD107 exhibited coagonist activity in the presence of ssRNA, while CU-CPD107 alone could not affect TLR8 signal transduction.
Smiles
C(C(C)(C)O)N1C(=C(I)N=C1COCC)C2=CC=CC=C2
Molecular Formula
C16H21IN2O2
Molecular Weight
400.25
Shipping Conditions
Cool pack
Storage Temperature
-20°C