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IHMT-PI3K-455

CAT: 0931-T78836-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T78836-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
PI3K
Related Pathways
PI3K/Akt/mTOR signaling
Bioactivity
IHMT-PI3K-455 (Compound 15u) is a potent, selective PI3Kγ/δ dual inhibitor with IC50 values of 7.1 nM for PI3Kγ and 0.57 nM for PI3Kδ, exhibiting oral activity. This compound inhibits AKT phosphorylation and promotes tumor regression by recruiting and activating CD8+ T cells. It is utilized in cancer research [1].
Molecular Formula
C26H21F2N7O3
Molecular Weight
517.49
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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