KY-455

• Target :

  E3 Ligase Ligand-Linker Conjugate|||Acyltransferase

• Related Pathways :

  PROTAC|||Metabolism

• Bioactivity :

  KY-455 is a novel acyl-CoA: cholesterol acyltransferase (ACAT) inhibitor. It demonstrates inhibition of ACAT in rabbit intestines, liver, macrophages, and adrenal glands with IC50 values of 0.4, 0.9, 2.9, and 4.1 ?mol/L, respectively.

• Smiles :

  O=C(NC1=C(C=C(C2=C1N(CC2)CCCCC)C)C)C(C)(C)C

• Molecular Formula :

  C20H32N2O

• Molecular Weight :

  316.48

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  178469-71-1