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IHMT-15130

CAT: 0804-HY-174142Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-174142Size:1 Each
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
IHMT-15130 is a highly potent irreversible BMX kinase inhibitor (IC50=1.47 nM) . IHMT-15130 inhibits the secretion of inflammatory cytokines, blocks inflammatory signaling pathways, and alleviates Angiotensin II-induced myocardial hypertrophy in mice. IHMT-15130 is promising for research of myocardial hypertrophy[1].
UNSPSC
12352005
Target
BMX Kinase
Related Pathways
Protein Tyrosine Kinase/RTK
Field of Research
Inflammation/Immunology; Cardiovascular Disease
Smiles
O=C(CC1=CC(NC(C=C)=O)=CC=C1)NC2=CNN=C2C3=NC4=CC(C(F)(F)F)=CC=C4N3
Molecular Formula
C22H17F3N6O2
Molecular Weight
454.40
References & Citations
[1]Qi S, et al. Discovery of IHMT-15130 as a Highly Potent Irreversible BMX Inhibitor for the Treatment of Myocardial Hypertrophy and Remodeling. ACS Chem Biol. 2025 May 19.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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