MTX-23

• CAS Number :

  2488296-74-6

• Target :

  Apoptosis|||PROTACs|||Androgen Receptor

• Related Pathways :

  Endocrinology/Hormones|||Apoptosis|||PROTAC

• Bioactivity :

  MTX-23, an AR-targeted Proteolysis Targeting Chimera (PROTAC), effectively degrades both AR-V7 and AR-FL, inhibiting the proliferation of CaP cells and inducing apoptosis [1].

• Smiles :

  O=C(NCCCCC(=O)N[C@@H](C(C)(C)C)C(=O)N1[C@@H](C[C@@H](O)C1)C(=O)N[C@@H](C)C2=CC=C(C=C2)C3=C(C)N=CS3)COC4=C(C=CC(F)=C4F)C5N=C(SC=5)N6CCOCC6

• Molecular Formula :

  C43H53F2N7O7S2

• Molecular Weight :

  882.05

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C