MTX-241F

• Target :

  EGFR|||PI3K

• Related Pathways :

  PI3K/Akt/mTOR signaling|||JAK/STAT signaling|||Angiogenesis|||Tyrosine Kinase/Adaptors

• Bioactivity :

  MTX-241F, a selective small molecule inhibitor, targets members of the EGFR and PI3 kinase families. It penetrates the blood-brain barrier, providing long-term tumor growth control and exhibits radiosensitizing activity in patient-derived DIPG neurospheres, potentially beneficial for studying diffuse intrinsic pontine glioma (DIPG) [1].

• Molecular Formula :

  C20H14ClFN6

• Molecular Weight :

  392.82

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C