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MTX-531

CAT: 1568-C03278-100mgSize: 100 mgDry Ice: NoHazardous: No
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CAT#:1568-C03278-100mgSize:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2791417-66-6
Synonyms
NSC827271
Target
EGFR
Applications
Protein Tyrosine Kinase
Molecular Formula
C22H20ClN5O2S
Additionnal Information
MTX-531 (NSC827271) is a first-in-class, potent and selective inhibitor of EGFR and PI3Kα with an IC50 of 14.7 nM and 6.4 nM, respectively. It may play a role in treating Head and Neck Squamous Cell Carcinoma (HSNCC), squamous lung cancers, and certain EGFR/PI3K-driven triple-negative breast cancers.