Antitumor agent-36

• Target :

  Apoptosis|||Others

• Related Pathways :

  Others|||Apoptosis

• Bioactivity :

  Antitumor agent-36 exhibits strong anti-proliferative and anti-metastasis capabilities, causing significant DNA damage that results in elevated levels of ?-H2AX and p53. It promotes tumor cell apoptosis via the mitochondrial apoptotic pathway involving Bcl-2/Bax/caspase3 and enhances immune response by inhibiting PD-L1 expression, thereby increasing CD3+ and CD8+ T cell infiltration in tumor tissues [1].

• Molecular Formula :

  C32H30Cl2N2O6Pt

• Molecular Weight :

  804.58

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C