TP-030-2

CAT: 0931-T73373-01Size: 25 mgDry Ice: NoHazardous: No

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CAT#:0931-T73373-01Size:25 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

2095514-84-2

Target

Serine Protease, Others, RIP kinase

Related Pathways

NF-κB, Others, Proteases/Proteasome, Apoptosis

Bioactivity

TP-030-2 is a RIPK1 inhibitor with a human Ki of 0.43 nM and a mouse IC50 of 100 nM.

Smiles

O=C1C=2C(=C(Br)N(CC3=CC=CC=C3)N2)CCN1[C@@H]4C(=O)N(C)C=5C(OC4)=CC=CC5

Molecular Formula

C23H21BrN4O3

Molecular Weight

481.34

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Chemical Information

CID 135309104

CAS Number	2095514-84-2
PubChem CID	135309104
IUPAC Name	(3S)-3-(2-benzyl-3-bromo-7-oxo-4,5-dihydropyrazolo[3,4-c]pyridin-6-yl)-5-methyl-2,3-dihydro-1,5-benzoxazepin-4-one
Molecular Formula	C23H21BrN4O3
Molecular Weight	481.3
XLogP	3.5
Topological Polar Surface Area	67.7
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	3
Heavy Atom Count	31
Formal Charge	0
Complexity	688

SMILES

CN1C2=CC=CC=C2OC[C@@H](C1=O)N3CCC4=C(N(N=C4C3=O)CC5=CC=CC=C5)Br

InChI

InChI=1S/C23H21BrN4O3/c1-26-17-9-5-6-10-19(17)31-14-18(22(26)29)27-12-11-16-20(23(27)30)25-28(21(16)24)13-15-7-3-2-4-8-15/h2-10,18H,11-14H2,1H3/t18-/m0/s1

InChIKey

KHVVJKLNKLQLJZ-SFHVURJKSA-N

Chemical Structure

2D Structure

CAS: 2095514-84-2

CID: 135309104

Formula: C23H21BrN4O3

MW: 481.3

Interactive 3D Structure

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View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	481.3
XLogP3	3.5
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	3
Exact Mass	480.07970
Monoisotopic Mass	480.07970
Topological Polar Surface Area	67.7 Å²
Heavy Atom Count	31
Formal Charge	0
Complexity	688
Isotope Atom Count	0
Defined Atom Stereocenter Count	1
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

Related Products

Catalog	Name
T73374-01	TP-030-1
T61521-01	NJH-2-030
T209311-01	TP-2
T5496-01	ML-030
T84478-01	JWH 030
T71417-01	LM-030
T69514-01	CLE-030
T87555-01	TP receptor antagonist-2
T208219-01	YX-02-030
T70429-01	TP-6076

Alternative Products

Catalog	Name
BA3514-10	TP-030-2
HY-148253	TP-030-1
HY-143348-01	NJH-2-030
HY-157930	TP-2
B8111-.1	2'-Deoxyzebularine-TP
MBS5758230	ML-030
MBS5812060	CLE-030
HY-P990670-01	TTX-030

TP-030-2

Chemical Information

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