TP-030-1

• Target :

  RIP kinase|||Others

• Related Pathways :

  Apoptosis|||NF-?B|||Others

• Bioactivity :

  TP-030-1, an inhibitor of RIPK1, exhibits potent activity against hRIPK1 (human RIPK1) with a Ki value of 3.9 nM and against mRIPK1 (mouse RIPK1) with an IC50 value of 4.2 ?M. This compound is instrumental in the research of inflammatory and neurodegenerative diseases.

• Smiles :

  O=C1C=2C(=CN(CC3=CC=CC=C3)N2)CCN1[C@@H]4C(=O)N(C)C=5C(OC4)=CC=CC5

• Molecular Formula :

  C23H22N4O3

• Molecular Weight :

  402.45

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2095514-75-1