JWH 030

• Target:

  Others

• Related Pathways:

  Others

• Bioactivity:

  JWH 030 is a potent naphthoyl pyrrole cannabimimetic, exhibiting higher affinity for the CB1 receptor (EC50= 30.5 nM in rats, Ki= 87 nM in mice) compared to CB2 (EC50= 552 nM in human CB2 receptors) . The compound demonstrates significant in vivo potency in mouse models, specifically in spontaneous activity and tail flick assays (antinociception) with an ED50 value of 26.8 ?M/kg. Furthermore, JWH 030 dose-dependently reduces electrically-induced contractions in the mouse vas deferens, with an IC50 of 3.38 nM, highlighting its effective modulatory effects. This compound is designated for forensic or research applications.

• Smiles:

  CCCCCn1ccc(c1)C(=O)c1cccc2ccccc12

• Molecular Formula:

  C20H21NO

• Molecular Weight:

  291.394

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  162934-73-8