JP-163-16

• Target:

  PROTACs|||Apoptosis|||NF-?B

• Related Pathways:

  Apoptosis|||PROTAC|||NF-?B

• Bioactivity:

  JP-163-16 is a RelA/p65 PROTAC degrader. It selectively reduces the expression of RelA/p65 in cells via a proteasome-dependent mechanism. JP-163-16 induces apoptosis by inhibiting the NF-?B signaling pathway. This compound is applicable for research on RelA/p65-dependent tumors, such as chronic lymphocytic leukemia (CLL) .

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C