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JP-163-16

CAT: 0931-T211198-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T211198-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Target
PROTACs, Apoptosis, NF-κB
Related Pathways
Apoptosis, PROTAC, NF-κB
Bioactivity
JP-163-16 is a RelA/p65 PROTAC degrader. It selectively reduces the expression of RelA/p65 in cells via a proteasome-dependent mechanism. JP-163-16 induces apoptosis by inhibiting the NF-κB signaling pathway. This compound is applicable for research on RelA/p65-dependent tumors, such as chronic lymphocytic leukemia (CLL) .
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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