JP-163-16

• Target :

  PROTACs|||Apoptosis|||NF-?B

• Related Pathways :

  Apoptosis|||PROTAC|||NF-?B

• Bioactivity :

  JP-163-16 is a RelA/p65 PROTAC degrader. It selectively reduces the expression of RelA/p65 in cells via a proteasome-dependent mechanism. JP-163-16 induces apoptosis by inhibiting the NF-?B signaling pathway. This compound is applicable for research on RelA/p65-dependent tumors, such as chronic lymphocytic leukemia (CLL) .

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C