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JP-11646

CAT: 0013-GTR19231834Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19231834Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
JP-11646 is a novel potent, selective, non-ATP competitive Pim2 inhibitor with IC50 of 0.5/1/24 nM for Pim2/3/1, respectively; shows less potency for other kinases in a kinase selectivity panel; exhibits 4-760-fold greater suppression of MM proliferation and viability than ATP-competitive PIM inhibitors; significant reduces tumor burden and increases median survival in xenogeneic myeloma murine models.
CAS Number
1902983-63-4
Purity
0.98
Notes
For research use only.

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