SKLB-163

• Target:

  Apoptosis|||Caspase|||Akt|||JNK|||MAPK|||Rho

• Related Pathways:

  Proteases/Proteasome|||Apoptosis|||Cytoskeletal Signaling|||MAPK|||PI3K/Akt/mTOR signaling|||Cell Cycle/Checkpoint

• Purity:

  0.9923

• Bioactivity:

  SKLB-163 acts by downregulating RhoGDI, activating JNK-1 signaling pathway and caspase-3, and reducing phosphorylated Akt and p44/42 MAPK.

• Smiles:

  S(CC(NCC1=CC=CC=C1)=O)C2=NC=3C(S2)=CC(NC(CCl)=O)=CC3

• Molecular Formula:

  C18H16ClN3O2S2

• Molecular Weight:

  405.92

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1255099-06-9