Antitumor agent-153

• Target:

  E1/E2/E3 Enzyme

• Related Pathways:

  Ubiquitination

• Bioactivity:

  Antitumor agent-153 (compound 11b) is an inhibitor of H2A histone ubiquitination, optimized from PRT4165. It can reduce the viability of human osteosarcoma U2OS cells and decrease monoubiquitination of histone H2A, demonstrating anticancer activity.

• Molecular Formula:

  C16H8N2O6

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C