ND-L11B TFA

• Target:

  Histone Methyltransferase

• Related Pathways:

  Chromatin/Epigenetic

• Bioactivity:

  ND-L11B TFA is a potent degrader of nuclear receptor binding SET domain protein 2 (NSD2) and RE-IIBP, with DC50 values of 1.48 ?M and 0.8 ?M, respectively, and a Dmax of approximately 80%.

• Smiles:

  C1C[C@@] (CN (C1) C2=CN=C (C=C2CN3C=NC4=C (N=CN=C43) N) C5=CC (=C (C=C5) F) OCC (=O) NCCCCCCCCCCCN) (CC (F) F) N.C (=O) (C (F) (F) F) O

• Molecular Formula:

  C39H52F6N10O4

• Molecular Weight:

  838.885

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C