ND-L11B TFA

• Target :

  Histone Methyltransferase

• Related Pathways :

  Chromatin/Epigenetic

• Bioactivity :

  ND-L11B TFA is a potent degrader of nuclear receptor binding SET domain protein 2 (NSD2) and RE-IIBP, with DC50 values of 1.48 ?M and 0.8 ?M, respectively, and a Dmax of approximately 80%.

• Smiles :

  C1C[C@@](CN(C1)C2=CN=C(C=C2CN3C=NC4=C(N=CN=C43)N)C5=CC(=C(C=C5)F)OCC(=O)NCCCCCCCCCCCN)(CC(F)F)N.C(=O)(C(F)(F)F)O

• Molecular Formula :

  C39H52F6N10O4

• Molecular Weight :

  838.885

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C