SMU-C68

• Target:

  NF-?B|||p38 MAPK|||TLR

• Related Pathways:

  Immunology/Inflammation|||MAPK|||NF-?B

• Bioactivity:

  SMU-C68 is a highly selective small molecule agonist of the TLR1/2 heterodimer (EC50=0.009 ?M) . It activates the NF-?B and MAPK pathways, leading to the release of pro-inflammatory cytokines such as TNF-? and IL-1?. SMU-C68 holds potential for cancer research applications.

• Smiles:

  O=C(OC(C)C)C1=C(SC2=C1CCC2)NC(=S)NC3=CC=CC4=NC=CC=C43

• Molecular Formula:

  C21H21N3O2S2

• Molecular Weight:

  411.54

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2677039-75-5