Products for Research Use Only

ND-L11B free base

CAT: 0931-T204108-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T204108-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Histone Methyltransferase
Related Pathways
Chromatin/Epigenetic
Bioactivity
ND-L11B is an effective degrader of the nuclear receptor binding SET domain protein 2 (NSD2) and RE-IIBP, with DC50 values of 1.48 μM and 0.8 μM, respectively, and a Dmax close to 80%.
Smiles
NC(N=CN=C12)=C1N=CN2CC3=CC(C4=CC(OCC(NCCCCCCCCCCCN)=O)=C(F)C=C4)=NC=C3N5C[C@](CC(F)F)(N)CCC5
Molecular Formula
C37H51F3N10O2
Molecular Weight
724.862
Shipping Conditions
Ice Packs
Storage Temperature
-20°C