SPP-DM1

• Target:

  Drug-Linker Conjugates for ADC

• Related Pathways:

  Antibody-drug Conjugate/ADC Related

• Bioactivity:

  SPP-DM1, a drug-linker conjugate for antibody-drug conjugates (ADC), demonstrates potent antitumor activity. It comprises DM1 (a potent microtubule-disrupting agent) connected through the ADC linker SPP[1].

• Smiles:

  [H][C@@]12C[C@@](O)(NC(=O)O1)[C@]([H])(OC)\C=C/C=C(C)\Cc1cc(OC)c(Cl)c(c1)N(C)C(=O)C[C@]([H])(OC(=O)[C@H](C)N(C)C(=O)CCSSC(C)CCC(=O)ON1C(=O)CCC1=O)[C@]1(C)O[C@H]1[C@@H]2C

• Molecular Formula:

  C44H59ClN4O14S2

• Molecular Weight:

  967.54

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  452072-20-7