RIPK1-IN-29

• Target:

  RIP kinase

• Related Pathways:

  Apoptosis|||NF-?B

• Bioactivity:

  RIPK1-IN-29 (Compound 22) is a RIPK1 inhibitor with an IC50 of 6.9 nM. It exhibits anti-necroptotic apoptosis activity by inhibiting RIPK1. In a TNF-? induced inflammatory in vivo model, a 10 mg/kg dose of RIPK1-IN-29 can protect mice from hypothermia and death. This compound is suitable for research in the field of inflammatory diseases.

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C