RIPK1-IN-29

CAT: 0931-T207005-01Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0931-T207005-01Size:10 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Target

RIP kinase

Related Pathways

Apoptosis, NF-κB

Bioactivity

RIPK1-IN-29 (Compound 22) is a RIPK1 inhibitor with an IC50 of 6.9 nM. It exhibits anti-necroptotic apoptosis activity by inhibiting RIPK1. In a TNF-α induced inflammatory in vivo model, a 10 mg/kg dose of RIPK1-IN-29 can protect mice from hypothermia and death. This compound is suitable for research in the field of inflammatory diseases.

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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RIPK1-IN-29

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