Products for Research Use Only

BMY 7378 free base

CAT: 0931-T206148-01Size: 10 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0931-T206148-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
21102-94-3
Target
Adrenergic Receptor, 5-HT Receptor
Related Pathways
Neuroscience, GPCR/G Protein
Bioactivity
BMY 7378 (free base) is a selective antagonist for the α1D adrenergic receptor (α1D-AR) . It exhibits a membrane-binding affinity for cloned rat α1D-AR (Ki=2 nM) that is over 100 times stronger than its affinity for cloned rat α1A-AR (Ki=800 nM) or hamster α1B-AR (Ki=600 nM) . Additionally, BMY 7378 (free base) acts as a partial agonist at the 5-HT1A receptor.
Smiles
O=C1N(C(=O)CC2(C1)CCCC2)CCN3CCN(C=4C=CC=CC4OC)CC3
Molecular Formula
C22H31N3O3
Molecular Weight
385.5
Shipping Conditions
Ice Packs
Storage Temperature
-20°C