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FLT3-ITD-IN-2

CAT: 0931-T203046-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T203046-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
FLT
Related Pathways
Tyrosine Kinase/Adaptors, Angiogenesis
Bioactivity
FLT3-ITD-IN-2 (Compound A1) is an inhibitor of the FLT3-ITD kinase, exhibiting an IC50 of 2.12 nM. It effectively suppresses the proliferation of the FLT3-dependent human AML cell line MOLM-13, with an IC50 of 25.65 nM. FLT3-ITD-IN-2 demonstrates antitumor activity against acute myeloid leukemia.
Molecular Formula
C39H50N8O6
Molecular Weight
726.86
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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