HDAC-IN-79

CAT: 0931-MF-0110277-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0110277-01Size:10 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Target
Apoptosis|||Autophagy|||Xanthine Oxidase|||HDAC
Related Pathways
Autophagy|||Chromatin/Epigenetic|||DNA Damage/DNA Repair|||Metabolism|||Apoptosis
Bioactivity
HDAC-IN-79 (compound 4) is an orally active dual inhibitor of xanthine oxidase and HDAC, exhibiting potent anti-hyperuricemia and antitumor activities in vivo (Xanthine oxidase: IC50=6.6 nM; HDAC1: IC50=134 nM; HDAC2: IC50=284 nM; HDAC3: IC50=173 nM; HDAC6: IC50=1.32 nM) . Among leukemia cells, it is most effective in inhibiting the growth of HL60 cells (IC50=0.706 ?M) and induces both apoptosis and autophagy. HDAC-IN-79 also modulates the expression levels of biomarkers associated with intracellular HDAC inhibition.
Shipping Conditions
Cool pack
Storage Temperature
-20°C

Related Products

CatalogName
MF-0022521-01HDAC-IN-5
MF-0140994-01HDAC-IN-30
MF-0140445-01HDAC-IN-46
MF-0052794-01HDAC-IN-47
MF-0020749-01HDAC-IN-44
MF-0146002-01HDAC-IN-6
MF-0015839-01HDAC-IN-7
MF-0037751-01HDAC-IN-32
MF-0039098-01HDAC-IN-34
MF-0118490-01HDAC-IN-91

Alternative Products

CatalogName
HY-162910HDAC-IN-79
sc-19602MECA-79 (MECA-79)
MBS3606681-01HDAC-IN-4
MBS5800347HDAC-IN-26
MBS5815358HDAC-IN-49
MBS5815367HDAC-IN-51
MBS5803953HDAC-IN-32
MBS5804331HDAC-IN-42
MBS5804608HDAC-IN-35
MBS5804697HDAC-IN-30

Popular Products