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MPO-IN-28

CAT: 0804-HY-115486-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-115486-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MPO-IN-28 is a selective myeloperoxidase (MPO) inhibitor with an IC50 of 44 nM. MPO-IN-28 can effectively inhibit MPO-mediated low-density lipoprotein oxidation with an IC50 of 90 nM[1].
CAS Number
37836-90-1
Product Name Alternative
NSC294845, 3M-852A
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Glutathione Peroxidase
Type
Reference compound
Related Pathways
Apoptosis; Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/mpo-in-28.html
Concentration
10mM
Purity
99.28
Solubility
DMSO : 12.5 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
NC(NC1=NC(C)=C2C=CC(OC)=CC2=N1)=N
Molecular Formula
C11H13N5O
Molecular Weight
231.25
Precautions
H302, H315, H319, H335
References & Citations
[1]Soubhye J, et al. Discovery of Novel Potent Reversible and Irreversible Myeloperoxidase Inhibitors Using Virtual Screening Procedure. J Med Chem. 2017 Aug 10;60 (15) :6563-6586.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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Alternative Products

CatalogName
T5340-01MPO-IN-28
A18941-200MPO-IN-28 200mg
A18941-10MPO-IN-28 10mg
A18941-100MPO-IN-28 100mg
A18941-5MPO-IN-28 5mg
A18941-50MPO-IN-28 50mg
A18941-25MPO-IN-28 25mg
A18941-2MPO-IN-28 2mg
A18941-1MPO-IN-28 1mg
A18941-10mM-DMPO-IN-28 10mM * 1mL in DMSO

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