Recombinant Mouse Max dimerization protein 1 (Mxd1)

CAT: 0399-CSB-BP015251MO-01Size: 20 µgDry Ice: NoHazardous: No

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CAT#:0399-CSB-BP015251MO-01Size:20 µg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Product Name Alternative

Protein MAD (Mad) (Mad1) (Max dimerizer 1)

Abbreviation

Recombinant Mouse Mxd1 protein

Gene Name

Mxd1

UniProt

P50538

Expression Region

1-227aa

Organism

Mus musculus (Mouse)

Target Sequence

MATAVGMNIQLLLEAADYLERREREAEHGYASMLPYSKDRDAFKRRNKPKKNSTSSRSTHNEMEKNRRAHLRLCLEKLKGLVPLGPESSRHTTLSLLTKAKLHIKKLEDCDRKAVHQIDQLQREQRHLKRRLEKLGAERTRMDSVGSVVSSERSDSDREELDVDVDVDVDVDVEGTDYLNGDLGWSSSVSDSDERGSMQSLGSDEGYSSATVKRAKLQDGHKAGLGL

Tag

N-terminal 10xHis-tagged and C-terminal Myc-tagged

Type

Developed Protein

Source

Baculovirus

Field of Research

Epigenetics and Nuclear Signaling

Relevance

Transcriptional repressor. MAD binds with MAX to form a sequence-specific DNA-binding protein complex which recognizes the core sequence 5'-CAC[GA]TG-3'. MAD thus antagonizes MYC transcriptional activity by competing for MAX.

Endotoxin

Not test

Purity

Greater than 85% as determined by SDS-PAGE.

Activity

Not Test

Form

Liquid or Lyophilized powder

Buffer

If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Function

Molecular Weight

29.6 kDa

References & Citations

"Mmip-2, a novel RING finger protein that interacts with mad members of the Myc oncoprotein network." Yin X.-Y., Gupta K., Prochownik E.V. Oncogene 18:6621-6634 (1999)

Storage Conditions

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Protein Length

Full Length

UniProtKB · P50538

Max dimerization protein 1

MAD1_MOUSE · Mus musculus

View on UniProt ↗

Primary accession: P50538
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: Mxd1
Protein existence: 1: Evidence at protein level
Organism: Mus musculus (Mouse)
Taxonomy ID: 10090
Alternative names: Max dimerizer 1
EC number: —
Processing: —
Secondary accessions: Q60798, Q61825

Protein keywords

Molecular function

DNA-bindingRepressor

Cellular component

Nucleus

Technical term

Reference proteome

Biological process

TranscriptionTranscription regulation

PTM

Ubl conjugation

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Alternative Products

Catalog	Name
MBS608088-01	MAX Dimerization Protein 1 (MXD1)
486345	MXD1 (Max Dimerization Protein 1)
MBS961338-01	Recombinant Mouse Max dimerization protein 1 (Mxd1)
abx235451	MAX Dimerization Protein 1 (MXD1) Antibody
038708	MXD1, NT (MXD1, MAD, Max dimerization protein 1, Protein MAD)
R1777m	Mouse Mxd1 / Max dimerization protein 1 Recombinant Protein
AE32193MO-01	Mouse Max dimerization protein 1 (MXD1) ELISA Kit
MBS6323080-01	MXD1, NT (MXD1, MAD, Max dimerization protein 1, Protein MAD) (FITC)
MBS6323077-01	MXD1, NT (MXD1, MAD, Max dimerization protein 1, Protein MAD) (AP)
BG-MUS11596	Mouse Max Dimerization Protein 1 Mxd1 ELISA Kit