RegisterLogin

AP-6

CAT: 0804-HY-161949-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-161949-01Size:5 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
AP-6 is a selective inhibitor of TMEM175 with activity in modulating lysosomal function. Acute inhibition of TMEM175 by AP-6 increases lysosomal macromolecular catabolism, thereby accelerating macrophage and other digestive processes. AP-6 may be used in Parkinson's disease research[1].
CAS Number
[1369963-51-8]
UNSPSC
12352005
Target
Potassium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ap-6.html
Purity
99.84
Solubility
DMSO : 0.93 mg/mL (ultrasonic; warming; adjust pH to 3 with 1 M HCL; heat to 60°C) |H2O : < 0.1 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
NC1=CC(C2=CC=CC(C3=CC(N)=CC=N3)=C2)=NC=C1
Molecular Formula
C16H14N4
Molecular Weight
262.31
References & Citations
[1]SeCheol, et al. "Discovery of Selective Inhibitors for the Lysosomal Parkinson’s Disease Channel TMEM175." Journal of the American Chemical Society (2024) .
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-153539AP-C3
HY-153540AP-C4
HY-14142AP-24226
HY-170310AP-238
HY-10363AP 24149
HY-153542AP-C6
HY-130530-01AP-C5
HY-153538-01AP-C2
HY-W014421-01AP-18
HY-P1419-01AP 811

Alternative Products

CatalogName
T200356-01AP-6
sc-136338AP-3σ (6)
MBS6482743-01Interleukin 6 (IL-6) (AP)
I8428-35B-APInterleukin 6 (IL-6) (AP) discontinued
MBS6134055-01Syntaxin 6 (Syntaxin-6, STX6) (AP)
MBS6242017-01Interleukin-6 (IL-6, IL6) (AP)
MBS6241547-01GRK 4-6 (AP)
MBS6260120-01Adenovirus, Type 6 (AP)
sc-136338 HRPAP-3σ (6) HRP
sc-390119AP-2β (C-6)

Popular Products