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AP-238

CAT: 0804-HY-170310Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-170310Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AP-238 is a a new synthetic opioid (NSO), and acts as an agonist for μ-opioid receptor (MOR) with an EC50 of 248 nM. AP-238 exhibits analgesic activity[1][2].
CAS Number
140924-11-4
UNSPSC
12352005
Target
Opioid Receptor
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Neurological Disease
Smiles
CCC(N1[C@H](C)CN(C/C=C/C2=CC=CC=C2)C[C@@H]1C)=O
Molecular Formula
C18H26N2O
Molecular Weight
286.41
References & Citations
[1]Jurowski K, et, al. Prediction of key toxicity endpoints of AP-238 a new psychoactive substance for clinical toxicology and forensic purposes using in silico methods. Sci Rep. 2024 Nov 22;14 (1) :28977.|[2]Brunetti P, et al., Human metabolism and basic pharmacokinetic evaluation of AP-238: A recently emerged acylpiperazine opioid. Drug Test Anal. 2024 Feb;16 (2) :221-235.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
μ Opioid Receptor/MOR

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