AP-238

• Description :

  AP-238 is a a new synthetic opioid (NSO), and acts as an agonist for μ-opioid receptor (MOR) with an EC50 of 248 nM. AP-238 exhibits analgesic activity[1][2].

• UNSPSC :

  12352005

• Target :

  Opioid Receptor

• Related Pathways :

  GPCR/G Protein; Neuronal Signaling

• Field of Research :

  Neurological Disease

• Smiles :

  CCC(N1[C@H](C)CN(C/C=C/C2=CC=CC=C2)C[C@@H]1C)=O

• Molecular Formula :

  C18H26N2O

• Molecular Weight :

  286.41

• References & Citations :

  [1]Jurowski K, et, al. Prediction of key toxicity endpoints of AP-238 a new psychoactive substance for clinical toxicology and forensic purposes using in silico methods. Sci Rep. 2024 Nov 22;14 (1) :28977.|[2]Brunetti P, et al., Human metabolism and basic pharmacokinetic evaluation of AP-238: A recently emerged acylpiperazine opioid. Drug Test Anal. 2024 Feb;16 (2) :221-235.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  μ Opioid Receptor/MOR

• CAS Number :

  [140924-11-4]