AP-C4

CAT: 0804-HY-153540Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-153540Size:1 Each
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Description
AP-C4 is an inhibitor of guanosine 3′,5′-cyclic monophosphate (cGMP) -dependent protein kinase II (cGKII) with a pIC50 of 5.2. AP-C3 does not inhibit cGKII-dependent anion secretion[1].
CAS Number
[682794-85-0]
UNSPSC
12352005
Target
PKG
Type
Reference compound
Related Pathways
Stem Cell/Wnt
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/ap-c4.html
Solubility
10 mM in DMSO
Smiles
C1(C2=CC3=C(OCCO3)C=C2)=NC(NCCC4=CNC5=C4C=CC=C5)=NC=C1
Molecular Formula
C22H20N4O2
Molecular Weight
372.42
References & Citations
[1]Marcel J C Bijvelds, et al. Selective inhibition of intestinal guanosine 3',5'-cyclic monophosphate signaling by small-molecule protein kinase inhibitors. J Biol Chem. 2018 May 25;293 (21) :8173-8181.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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