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AP-C5

CAT: 0804-HY-130530-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-130530-01Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AP-C5 displays selective inhibition of guanosine 3′,5′-cyclic monophosphate (cGMP) -dependent protein kinase II (cGKII) with a pIC50 of 7.2, which can be used for the research of diarrheal disease[1]. AP-C5 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
CAS Number
[2234272-10-5]
UNSPSC
12352005
Target
Biochemical Assay Reagents
Type
Reference compound
Related Pathways
Others
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/ap-c5.html
Purity
98.14
Solubility
DMSO : 25 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
C#CCNC1=NC=CC(C2=CC=C(N3C=CN=C3)C=C2)=N1
Molecular Formula
C16H13N5
Molecular Weight
275.31
References & Citations
[1]Marcel J C Bijvelds, et al. Selective inhibition of intestinal guanosine 3',5'-cyclic monophosphate signaling by small-molecule protein kinase inhibitors. J Biol Chem. 2018 May 25;293 (21) :8173-8181.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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