AP-C5

• UNSPSC Description:

  AP-C5 displays selective inhibition of guanosine 3′,5′-cyclic monophosphate (cGMP)-dependent protein kinase II (cGKII) with a pIC50 of 7.2, which can be used for the research of diarrheal disease[1]. AP-C5 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

• Target Antigen:

  Biochemical Assay Reagents

• Type:

  Reference compound

• Related Pathways:

  Others

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/ap-c5.html

• Purity:

  98.14

• Solubility:

  DMSO : 25 mg/mL (ultrasonic;warming;heat to 60°C)

• Smiles:

  C#CCNC1=NC=CC(C2=CC=C(N3C=CN=C3)C=C2)=N1

• Molecular Weight:

  275.31

• References & Citations:

  [1]Marcel J C Bijvelds, et al. Selective inhibition of intestinal guanosine 3',5'-cyclic monophosphate signaling by small-molecule protein kinase inhibitors. J Biol Chem. 2018 May 25;293(21):8173-8181.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  2234272-10-5