AP-C2

• Description :

  AP-C2 is a potent guanosine 3',5'-cyclic monophosphate (cGMP) -dependent protein kinase II (cGKII) inhibitor with a pIC50 of 5.2[1].

• UNSPSC :

  12352005

• Target :

  Ser/Thr Protease

• Type :

  Reference compound

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  Metabolism-protein/nucleotide metabolism

• Field of Research :

  Metabolic Disease

• Assay Protocol :

  https://www.medchemexpress.com/ap-c2.html

• Solubility :

  10 mM in DMSO

• Smiles :

  C1(C2=CC=CS2)=CC=NC(NCCC3=CNC4=C3C=CC=C4)=N1

• Molecular Formula :

  C18H16N4S

• Molecular Weight :

  320.41

• References & Citations :

  [1]Marcel J C Bijvelds, et al. Selective inhibition of intestinal guanosine 3',5'-cyclic monophosphate signaling by small-molecule protein kinase inhibitors. J Biol Chem. 2018 May 25;293 (21) :8173-8181.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [682793-07-3]