AP-C2

• Description:

  AP-C2 is a potent guanosine 3',5'-cyclic monophosphate (cGMP) -dependent protein kinase II (cGKII) inhibitor with a pIC50 of 5.2[1].

• UNSPSC:

  12352005

• Target:

  Ser/Thr Protease

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/ap-c2.html

• Solubility:

  10 mM in DMSO

• Smiles:

  C1(C2=CC=CS2)=CC=NC(NCCC3=CNC4=C3C=CC=C4)=N1

• Molecular Formula:

  C18H16N4S

• Molecular Weight:

  320.41

• References & Citations:

  [1]Marcel J C Bijvelds, et al. Selective inhibition of intestinal guanosine 3',5'-cyclic monophosphate signaling by small-molecule protein kinase inhibitors. J Biol Chem. 2018 May 25;293 (21) :8173-8181.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [682793-07-3]