Products for Research Use Only
RegisterLogin

MAP3K8 (phospho Ser400) Antibody

CAT: 0223-79-852Size: 0.1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0223-79-852Size:0.1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
This gene was identified by its oncogenic transforming activity in cells. The encoded protein is a member of the serine/threonine protein kinase family. This kinase can activate both the MAP kinase and JNK kinase pathways. This kinase was shown to activate IkappaB kinases, and thus induce the nuclear production of NF-kappaB. This kinase was also found to promote the production of TNF-alpha and IL-2 during T lymphocyte activation. Studies of a similar gene in rat suggested the direct involvement of this kinase in the proteolysis of NF-kappaB1, p105 (NFKB1) .
NCBI Gene ID
1326
Swiss Prot
P41279
Accession Number
NP_001231063.1
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
MAP3K8 (phospho Ser400) antibody was raised against a peptide sequence around phosphorylation site of Serine 400 (C-Q-S (p) -L-D) derived from HumanMAP3K8.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Phospho-Specific
Purification
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Concentration
1 mg/mL
Buffer
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Modification
Phospho-Specific
Shipping Conditions
Blue Ice
Storage Conditions
Store antibody at -20˚ C for up to one year.
Calculated Molecular Weight
52 kDa
Fragment
IgG
Specificity
The antibody detects endogenous levels of MAP3K8 only when phosphorylated at serine 400.
Symbol
MAP3K8
NCBI Official Name
Mitogen-activated protein kinase kinase kinase 8
NCBI Organism
Homo sapiens
Background Reference 01
Miyoshi J., Mol. Cell. Biol. 11:4088-4096 (1991) .
Background Reference 02
Aoki M., J. Biol. Chem. 268:22723-22732 (1993) .
Background Reference 03
Chan A.M., Oncogene 8:1329-1333 (1993) .
Other Product Names
C-COT; , M3K8, MAP3K8, TPL2
Tested Applications
IHC
Protein ID
22035598
Physical Properties
Liquid

Related Products

CatalogName
16-144MAP3K8 Antibody
27-310MAP3K8 Antibody
79-812GATA2 (phospho Ser401) Antibody
79-443MyoD (phospho Ser200) Antibody
79-153Tau (phospho Ser404) Antibody
79-851MAP3K1 (phospho Thr1402) Antibody
50-247Parkin (phospho Ser101) Antibody
79-141EGFR (phospho Ser1070) Antibody
79-928YB1 (phospho Ser102) Antibody
79-919CNOT2 (phospho Ser101) Antibody

Alternative Products

CatalogName
OASG01773-100ULMAP3K8 Antibody (Phospho-Ser400)
8A8134-AATMAP3K8 (Phospho-Ser400) Antibody
MBS7133132-01Phospho-MAP3K8 (Ser400) Antibody
MBS9614462-01Phospho-MAP3K8/COT (Ser400) Antibody
bs-3454RPhospho-MAP3K8 (Ser400) Polyclonal Antibody
70R-32674MAP3K8 antibody (Ser400)
E47R3454Phospho-MAP3K8 (Ser400) Rabbit pAb
AF8469-BPPhospho-MAP3K8/COT (Ser400) Peptide
GTR18997155Phospho-MAP3K8 (Ser400) Antibody Blocking Peptide
TMAC-02461-01Anti-Phospho-MAP3K8 (Ser400) Polyclonal Antibody

Popular Products