EIF4A2 Antibody

CAT: 0223-63-830Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-63-830Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Eukaryotic initiation factor 4A plays an important role in the binding of mRNA to the 43S preinitiation complex when protein synthesis begins. Two highly homologous forms of functional EIF4A genes, Eif4a1 and Eif4a2, have been isolated in mice; yeast cells also possess 2 EIF4A genes, TIF1 and TIF2. The murine Eif4a and yeast TIF genes appear to belong to a DEAD-box gene family, whose members exhibit extensive amino acid similarity and contain the asp-glu-ala-asp (DEAD) sequence. DEAD-box genes have been identified in species ranging from E-coli to humans. Their function appears to be related to transcriptional/translational regulation (referenced from OMIM) .
NCBI Gene ID
1974
Swiss Prot
Q14240
Accession Number
Q14240
Host
Rabbit
Reactivity
Human
Immunogen
This EIF4A2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 333-360 amino acids from the C-terminal region of human EIF4A2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Monkey, Mouse, Rabbit, Chicken, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
46 kDa
Fragment
Rabbit Ig
Symbol
EIF4A2
NCBI Official Name
Eukaryotic initiation factor 4A-II
NCBI Organism
Homo sapiens
Background Reference 01
Martins-de-Souza, D., et.al., Neural Transm 116 (3), 275-289 (2009)
Background Reference 02
Lin, C.J., et.al., Cancer Res. 68 (13), 5326-5334 (2008)
Other Product Names
Eukaryotic initiation factor 4A-II, eIF-4A-II, eIF4A-II, ATP-dependent RNA helicase eIF4A-2, EIF4A2, DDX2B, EIF4F
Tested Applications
WB, IHC-P, Flow
Protein ID
45645183
Physical Properties
Liquid

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