EIF5A2 Antibody

• Background:

  MRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis. Mediates effects of polyamines on neuronal process extension and survival. May play an important role in brain development and function, and in skeletal muscle stem cell differentiation (By similarity) .

• NCBI Gene ID:

  56648

• Swiss Prot:

  Q9GZV4

• Accession Number:

  Q9GZV4

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This EIF5A2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 93-122 amino acids from the C-terminal region of human EIF5A2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Mouse

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  17 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  EIF5A2

• NCBI Official Name:

  Eukaryotic translation initiation factor 5A-2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Tang, D.J., et al. Hepatology 51 (4) :1255-1263 (2010)

• Background Reference 02:

  Luo, J.H., et al. Cancer Sci. 100 (5) :896-902 (2009)

• Background Reference 03:

  Chen, W., et al. Cancer Epidemiol. Biomarkers Prev. 18 (2) :400-408 (2009)

• Background Reference 04:

  Yang, G.F., et al. Gynecol. Oncol. 112 (2) :314-318 (2009)

• Other Product Names:

  Eukaryotic translation initiation factor 5A-2, eIF-5A-2, eIF-5A2, Eukaryotic initiation factor 5A isoform 2, EIF5A2

• Tested Applications:

  WB, IHC-P

• Protein ID:

  74762725

• Physical Properties:

  Liquid