EIF4A3 Antibody

• Background :

  This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene is a nuclear matrix protein. Its amino acid sequence is highly similar to the amino acid sequences of the translation initiation factors eIF4AI and eIF4AII, two other members of the DEAD box protein family.

• NCBI Gene ID :

  9775

• Swiss Prot :

  P38919

• Accession Number :

  P38919

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  This EIF4A3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 297-325 amino acids from the C-terminal region of human EIF4A3.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Other

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Homology :

  Predicted species reactivity based on immunogen sequence: Xenopus, Bovine, Chicken, Zebrafish, Monkey, Mouse, Pig, Rat

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  47 kDa

• Fragment :

  Rabbit Ig

• Applications Notes :

  For WB starting dilution is: 1:1000

• Symbol :

  EIF4A3

• NCBI Official Name :

  Eukaryotic initiation factor 4A-III

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Koroleva, O.A., et al. Plant Cell 21 (5) :1592-1606 (2009)

• Background Reference 02 :

  Karam, R., et al. Oncogene 27 (30) :4255-4260 (2008)

• Background Reference 03 :

  Ma, X.M., et al. Cell 133 (2) :303-313 (2008)

• Background Reference 04 :

  Giorgi, C., et al. Cell 130 (1) :179-191 (2007)

• Other Product Names :

  Eukaryotic initiation factor 4A-III, eIF-4A-III, eIF4A-III, ATP-dependent RNA helicase DDX48, ATP-dependent RNA helicase eIF4A-3, DEAD box protein 48, Eukaryotic initiation factor 4A-like NUK-34, Eukaryotic translation initiation factor 4A isoform 3, Nuclear matrix protein 265, NMP 265, hNMP 265, Eukaryotic initiation factor 4A-III, N-terminally processed, EIF4A3, DDX48, KIAA0111

• Tested Applications :

  WB

• Protein ID :

  20532400

• Physical Properties :

  Liquid