EIF4A3 Antibody

CAT: 0223-60-471Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-60-471Size:400 µL
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Background
This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene is a nuclear matrix protein. Its amino acid sequence is highly similar to the amino acid sequences of the translation initiation factors eIF4AI and eIF4AII, two other members of the DEAD box protein family.
NCBI Gene ID
9775
Swiss Prot
P38919
Accession Number
P38919
Host
Rabbit
Reactivity
Human
Immunogen
This EIF4A3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 297-325 amino acids from the C-terminal region of human EIF4A3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Xenopus, Bovine, Chicken, Zebrafish, Monkey, Mouse, Pig, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
47 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
EIF4A3
NCBI Official Name
Eukaryotic initiation factor 4A-III
NCBI Organism
Homo sapiens
Background Reference 01
Koroleva, O.A., et al. Plant Cell 21 (5) :1592-1606 (2009)
Background Reference 02
Karam, R., et al. Oncogene 27 (30) :4255-4260 (2008)
Background Reference 03
Ma, X.M., et al. Cell 133 (2) :303-313 (2008)
Background Reference 04
Giorgi, C., et al. Cell 130 (1) :179-191 (2007)
Other Product Names
Eukaryotic initiation factor 4A-III, eIF-4A-III, eIF4A-III, ATP-dependent RNA helicase DDX48, ATP-dependent RNA helicase eIF4A-3, DEAD box protein 48, Eukaryotic initiation factor 4A-like NUK-34, Eukaryotic translation initiation factor 4A isoform 3, Nuclear matrix protein 265, NMP 265, hNMP 265, Eukaryotic initiation factor 4A-III, N-terminally processed, EIF4A3, DDX48, KIAA0111
Tested Applications
WB
Protein ID
20532400
Physical Properties
Liquid

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