EIF4E2 Antibody

• Background:

  EIF4E2 is expressed exclusively in the cytoplasm. This protein recognizes and binds the 7 methylguanosine containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures.

• NCBI Gene ID:

  9470

• Swiss Prot:

  O60573

• Accession Number:

  O60573

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This EIF4E2 antibody is generated from rabbits immunized with human EIF4E2 recombinant protein.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  28 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  EIF4E2

• NCBI Official Name:

  Eukaryotic translation initiation factor 4E type 2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Rom, E., et al., J. Biol. Chem. 273 (21) :13104-13109 (1998) .

• Background Reference 02:

  Mao, M., et al., Proc. Natl. Acad. Sci. U.S.A. 95 (14) :8175-8180 (1998) .

• Background Reference 03:

  Tee, A.R., et al., FEBS Lett. 564 (1-2), 58-62 (2004) () : () .

• Other Product Names:

  Eukaryotic translation initiation factor 4E type 2, eIF-4E type 2, eIF4E type 2, Eukaryotic translation initiation factor 4E homologous protein, Eukaryotic translation initiation factor 4E-like 3, eIF4E-like protein 4E-LP, mRNA cap-binding protein 4EHP, mRNA cap-binding protein type 3, EIF4E2, EIF4EL3

• Tested Applications:

  WB, IHC-P

• Physical Properties:

  Liquid