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CPSF6 Antibody

CAT: 0223-60-961Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-60-961Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is one subunit of a cleavage factor required for 3' RNA cleavage and polyadenylation processing. The interaction of the protein with the RNA is one of the earliest steps in the assembly of the 3' end processing complex and facilitates the recruitment of other processing factors. The cleavage factor complex is composed of four polypeptides. This gene encodes the 68kD subunit. It has a domain organization reminiscent of spliceosomal proteins.
NCBI Gene ID
11052
Swiss Prot
Q16630
Accession Number
Q16630
Host
Rabbit
Reactivity
Human
Immunogen
This CPSF6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 23-51 amino acids from the N-terminal region of human CPSF6.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Chicken, Zebrafish, Mouse, Xenopus
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
59 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
CPSF6
NCBI Official Name
Cleavage and polyadenylation specificity factor subunit 6
NCBI Organism
Homo sapiens
Background Reference 01
Lee, K., et al. Cell Host Microbe 7 (3) :221-233 (2010)
Background Reference 02
Ruepp, M.D., et al. Mol. Biol. Cell 20 (24) :5211-5223 (2009)
Background Reference 03
Xin, X., et al. Genome Res. 19 (7) :1262-1269 (2009)
Background Reference 04
Maggi, L.B. Jr., et al. Mol. Cell. Biol. 28 (23) :7050-7065 (2008)
Other Product Names
Cleavage and polyadenylation specificity factor subunit 6, Cleavage and polyadenylation specificity factor 68 kDa subunit, CFIm68, CPSF 68 kDa subunit, Pre-mRNA cleavage factor Im 68 kDa subunit, Protein HPBRII-4/7, CPSF6, CFIM68
Tested Applications
WB
Protein ID
88909266
Physical Properties
Liquid

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