CPSF3 Antibody

• Background:

  CPSF3 belongs to the RNA-metabolizing metallo-beta-lactamase-like family, CPSF3 subfamily. It is component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly (A) polymerase and other factors to bring about cleavage and poly (A) addition.

• NCBI Gene ID:

  51692

• Swiss Prot:

  Q9UKF6

• Accession Number:

  NP_057291

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat, Dog, Zebrafish

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CPSF3.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer

• Purification:

  Antibody is purified by protein A chromatography method.

• Positive Control:

  Cat. No. 1205 - Jurkat Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store CPSF3 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  75 kDa

• Applications Notes:

  CPSF3 antibody can be used for detection of CPSF3 by ELISA at 1:312500. CPSF3 antibody can be used for detection of CPSF3 by western blot at 5.0 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  CPSF3

• NCBI Official Name:

  Cleavage and polyadenylation specific factor 3, 73kDa

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Calzado, M.A., (2004) J. Virol. 78 (13), 6846-6854.

• Other Product Names:

  CPSF3, CPSF73, CPSF-73

• Tested Applications:

  ELISA, WB

• Protein ID:

  7706427

• Physical Properties:

  Liquid