CPSF1 Antibody

• Background :

  CPSF1 is a component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly (A) polymerase and other factors to bring about cleavage and poly (A) addition. This subunit is involved in the RNA recognition step of the polyadenylation reaction.

• NCBI Gene ID :

  29894

• Swiss Prot :

  Q10570

• Accession Number :

  NP_037423

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CPSF1.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Other

• Purification :

  Antibody is purified by peptide affinity chromatography method.

• Positive Control :

  Tranfected 293T Cell Lysate

• Concentration :

  Batch dependent

• Buffer :

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store CPSF1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight :

  161 kDa

• Applications Notes :

  CPSF1 antibody can be used for detection of CPSF1 by ELISA at 1:62500. CPSF1 antibody can be used for detection of CPSF1 by western blot at 0.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol :

  CPSF1

• NCBI Official Name :

  Cleavage and polyadenylation specific factor 1, 160kDa

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Beausoleil, S.A., (2004) Proc. Natl. Acad. Sci. U.S.A. 101 (33), 12130-12135.

• Other Product Names :

  CPSF1, CPSF160, HSU37012, P/cl.18

• Tested Applications :

  ELISA, WB

• Protein ID :

  56676371

• Physical Properties :

  Liquid