CPSF2 Antibody

• Background:

  CPSF2 is a component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly (A) polymerase and other factors to bring about cleavage and poly (A) addition. It belongs to the metallo-beta-lactamase superfamily, RNA-metabolizing metallo-beta-lactamase-like family, CPSF2/YSH1 subfamily.

• NCBI Gene ID:

  53981

• Swiss Prot:

  Q9P2I0

• Accession Number:

  NP_059133

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CPSF2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  Antibody is purified by peptide affinity chromatography method.

• Positive Control:

  Cat. No. 1301 - Human Heart Tissue Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store CPSF2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  88 kDa

• Applications Notes:

  CPSF2 antibody can be used for detection of CPSF2 by ELISA at 1:62500. CPSF2 antibody can be used for detection of CPSF2 by western blot at 0.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  CPSF2

• NCBI Official Name:

  Cleavage and polyadenylation specific factor 2, 100kDa

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Ewing, R.M., Mol. Syst. Biol. 3, 89 (2007) .

• Other Product Names:

  CPSF2, CPSF100, KIAA1367

• Tested Applications:

  ELISA, WB

• Protein ID:

  34101288

• Physical Properties:

  Liquid