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CPSF3 Antibody

CAT: 0223-58-002Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-58-002Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Most eukaryotic mRNA precursors (pre-mRNAs) undergo extensive maturational processing, including cleavage and polyadenylation at the 3-prime end. CPSF3 encodes the 73-kD subunit of the cleavage and polyadenylation specificity factor (CPSF) and is the pre-mRNA 3-prime-end-processing endonuclease (Mandel et al., 2006 [PubMed 17128255]) .
NCBI Gene ID
51692
Swiss Prot
Q9UKF6
Accession Number
Q9UKF6
Host
Rabbit
Reactivity
Human
Immunogen
This CPSF3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 192-221 amino acids from the Central region of human CPSF3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
77 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
CPSF3
NCBI Official Name
Cleavage and polyadenylation specificity factor subunit 3
NCBI Organism
Homo sapiens
Background Reference 01
Rozenblatt-Rosen, O., et al. Proc. Natl. Acad. Sci. U.S.A. 106 (3) :755-760 (2009)
Background Reference 02
Zhu, Z.H., et al. Oncogene 28 (1) :41-51 (2009)
Background Reference 03
Yang, X.C., et al. Mol. Cell. Biol. 29 (1) :31-42 (2009)
Background Reference 04
Kolev, N.G., et al. EMBO Rep. 9 (10) :1013-1018 (2008)
Other Product Names
Cleavage and polyadenylation specificity factor subunit 3, 3127-, Cleavage and polyadenylation specificity factor 73 kDa subunit, CPSF 73 kDa subunit, mRNA 3'-end-processing endonuclease CPSF-73, CPSF3, CPSF73
Tested Applications
WB
Protein ID
18203503
Physical Properties
Liquid

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