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EIF4E Antibody

CAT: 0223-60-601Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-60-601Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
EIF4E is a eukaryotic translation initiation factor involved in directing ribosomes to the cap structure of mRNAs. It is a 24-kD polypeptide that exists as both a free form and as part of a multiprotein complex termed EIF4F. The EIF4E polypeptide is the rate-limiting component of the eukaryotic translation apparatus and is involved in the mRNA-ribosome binding step of eukaryotic protein synthesis. The other subunits of EIF4F are a 50-kD polypeptide, termed EIF4A (see MIM 601102), that possesses ATPase and RNA helicase activities, and a 220-kD polypeptide, EIF4G.
NCBI Gene ID
1977
Swiss Prot
P06730
Accession Number
P06730
Host
Rabbit
Reactivity
Human
Immunogen
This EIF4E antibody is generated from rabbits immunized with a recombinant protein from human VGFR2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
25 kDa
Fragment
Rabbit Ig
Symbol
EIF4E
NCBI Official Name
Eukaryotic translation initiation factor 4E
NCBI Organism
Homo sapiens
Background Reference 01
Kim, S., et.al., J. Virol. 84 (1), 52-58 (2010)
Background Reference 02
Kao, C.L., et.al., Cancer Lett. 286 (2), 250-259 (2009)
Other Product Names
Eukaryotic translation initiation factor 4E, eIF-4E, eIF4E, eIF-4F 25 kDa subunit, mRNA cap-binding protein, EIF4E, EIF4EL1, EIF4F
Tested Applications
WB, IHC-P, Flow
Protein ID
1352435
Physical Properties
Liquid

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