EIF4E Antibody

• Background :

  The protein encoded by this gene is a component of the eukaryotic translation initiation factor 4F complex, which recognizes the 7-methylguanosine cap structure at the 5' end of messenger RNAs. The encoded protein aids in translation initiation by recruiting ribosomes to the 5'-cap structure. Association of this protein with the 4F complex is the rate-limiting step in translation initiation. This gene acts as a proto-oncogene, and its expression and activation is associated with transformation and tumorigenesis. Several pseudogenes of this gene are found on other chromosomes. Alternative splicing results in multiple transcript variants.

• NCBI Gene ID :

  1977

• Swiss Prot :

  P06730

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  A synthetic peptide corresponding to a sequence within amino acids 1-100 of human EIF4E (NP_001959.1) .

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Immunology, Signal Transduction

• Purification :

  Affinity purification

• Positive Control :

  HL-60

• Concentration :

  Batch dependent

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  Observed: 25kDa

• Fragment :

  IgG

• Symbol :

  EIF4E

• Positive Control 2 :

  SW620

• Positive Control 3 :

  MCF-7

• Positive Control 4 :

  293T

• Positive Control 5 :

  Mouse brain

• Positive Control 6 :

  Rat testis

• NCBI Official Name :

  Eukaryotic translation initiation factor 4E

• NCBI Organism :

  Homo sapiens

• Other Product Names :

  Eukaryotic translation initiation factor 4E, eIF-4E, eIF4E, eIF-4F 25 kDa subunit, mRNA cap-binding protein, EIF4E, EIF4EL1, EIF4F

• Tested Applications :

  WB, IHC, IF, IP

• Physical Properties :

  Liquid