Mouse Ptk2b Antibody

• Background :

  Involved in calcium induced regulation of ion channel and activation of the map kinase signaling pathway. May represent an important signaling intermediate between neuropeptide activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. Interacts with the SH2 domain of Grb2. May phosphorylate the voltage-gated potassium channel protein Kv1.2. Its activation is highly correlated with the stimulation of c-Jun N-terminal kinase activity. Involved in osmotic stress-dependent SNCA 'Tyr-125' phosphorylation (By similarity) .

• NCBI Gene ID :

  19229

• Swiss Prot :

  Q9QVP9

• Accession Number :

  Q9QVP9

• Host :

  Rabbit

• Reactivity :

  Human, Mouse

• Immunogen :

  This Mouse Ptk2b antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 672-701 amino acids from the Central region of mouse Ptk2b.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Cancer, Signal Transduction

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  116 kDa

• Fragment :

  Rabbit Ig

• Symbol :

  Ptk2b

• NCBI Official Name :

  Protein-tyrosine kinase 2-beta

• NCBI Organism :

  Mus musculus

• Other Product Names :

  Protein-tyrosine kinase 2-beta, Calcium-dependent tyrosine kinase, CADTK, Calcium-regulated non-receptor proline-rich tyrosine kinase, Cell adhesion kinase beta, CAK-beta, CAKB, Focal adhesion kinase 2, FADK 2, Proline-rich tyrosine kinase 2, Related adhesion focal tyrosine kinase, RAFTK, Ptk2b, Fak2, Pyk2, Raftk

• Tested Applications :

  WB, IHC-P

• Physical Properties :

  Liquid