Products for Research Use Only

Mouse Dnmt3L Antibody

CAT: 0223-55-295Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-55-295Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
MDnmt3L (DNA methyltransferase 3L) does not appear to be catalytically active due to loss of the critical active site residues. It may function not directly as a DNA methyltransferase but rather as a regulator of methylation at imprinted loci. It is required specifically for the establishment of genomic imprints but is dispensable for their propagation. It is essential for the de novo methylation of single-copy DNA sequences. The protein is well-express in testis, thymus, ovary, and heart. mDnmt3L, which belongs to the 5-cytosine methyltransferase family, contains 1 ADD-type zinc finger.
NCBI Gene ID
54427
Swiss Prot
Q9CWR8
Accession Number
Q9CWR8
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This Mouse Dnmt3L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 389-421 amino acids from mouse Dnmt3L.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
48 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
Dnmt3l
NCBI Official Name
DNA (cytosine-5) -methyltransferase 3-like
NCBI Organism
Mus musculus
Background Reference 01
Okazaki, Y., et al., Nature 420 (6915) :563-573 (2002) .
Background Reference 02
Bourc'his, D., et al., Science 294 (5551) :2536-2539 (2001) .
Background Reference 03
Aapola, U., et al., Cytogenet. Cell Genet. 92 (1-2), 122-126 (2001) .
Other Product Names
DNA (cytosine-5) -methyltransferase 3-like, Dnmt3l
Tested Applications
WB
Physical Properties
Liquid