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Mouse Dnmt2 Antibody

CAT: 0223-55-291Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-55-291Size:400 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
MDnmt2 does not appear to be active as a DNA methyltransferase; however, its strong binding to DNA suggests that it may mark specific sequences in the genome by binding to DNA through the specific target-recognizing motif. mDnmt2 is strongly expressed in thymus, testis, and at much lower levels in spleen, lung, brain, heart, kidney, liver, skeletal muscle and embryonic stem cells. This protein belongs to the 5-cystosine methyltransferase family.
NCBI Gene ID
13434
Swiss Prot
O55055
Accession Number
O55055
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This Mouse Dnmt2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 201-230 amino acids from the N-terminal region of mouse Dnmt2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
47 kDa
Fragment
Rabbit Ig
Symbol
Trdmt1
NCBI Official Name
TRNA (cytosine (38) -C (5) ) -methyltransferase
NCBI Organism
Mus musculus
Background Reference 01
Yoder, J.A., et al., Hum. Mol. Genet. 7 (2) :279-284 (1998) .
Background Reference 02
Okano, M., et al., Nucleic Acids Res. 26 (11) :2536-2540 (1998) .
Other Product Names
TRNA (cytosine (38) -C (5) ) -methyltransferase, DNA (cytosine-5) -methyltransferase-like protein 2, Dnmt2, DNA methyltransferase homolog MmuIIP, DNA MTase homolog MmuIIP, MMmuIIP, Met-2, Trdmt1, Dnmt2, Met2
Tested Applications
WB, IHC-P
Physical Properties
Liquid

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