PTK2 Antibody

• Background :

  PTK2 is a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. This protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies.

• NCBI Gene ID :

  5747

• Swiss Prot :

  Q05397

• Accession Number :

  Q05397

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  This PTK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 396-423 amino acids from the Central region of human PTK2.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Cancer, Signal Transduction

• Purification :

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration :

  Batch dependent

• Homology :

  Predicted species reactivity based on immunogen sequence: Rat, Chicken

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  119 kDa

• Fragment :

  Rabbit Ig

• Symbol :

  PTK2

• NCBI Official Name :

  Focal adhesion kinase 1

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Calalb, M.B., et.al., Mol. Cell. Biol. 15 (2), 954-963 (1995)

• Background Reference 02 :

  Polte, T.R. et.al., Proc. Natl. Acad. Sci. U.S.A. 92 (23), 10678-10682 (1995)

• Background Reference 03 :

  Gervais, F.G., et.al., J. Biol. Chem. 273 (27), 17102-17108 (1998)

• Other Product Names :

  Focal adhesion kinase 1, FADK 1, Focal adhesion kinase-related nonkinase, FRNK, Protein phosphatase 1 regulatory subunit 71, PPP1R71, Protein-tyrosine kinase 2, p125FAK, pp125FAK, PTK2, FAK, FAK1

• Tested Applications :

  WB, IHC-P, IF, Flow

• Protein ID :

  3183518

• Physical Properties :

  Liquid