Mouse Jak3 Antibody

• Background:

  Tyrosine kinase of the non-receptor type, involved in the interleukin-2 and interleukin-4 signaling pathway. Phosphorylates STAT6, IRS1, IRS2 and PI3K.

• NCBI Gene ID:

  16453

• Swiss Prot:

  Q62137

• Accession Number:

  Q62137

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  This Mouse Jak3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 133-161 amino acids from the N-terminal region of mouse Jak3.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  123 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  Jak3

• NCBI Official Name:

  Tyrosine-protein kinase JAK3

• NCBI Organism:

  Mus musculus

• Background Reference 01:

  Martin, P., et al. Mol. Cell. Biol. 30 (20) :4877-4889 (2010)

• Background Reference 02:

  Lange, C., et al. J. Neurochem. 113 (5) :1210-1220 (2010)

• Background Reference 03:

  Shi, M., et al. J. Immunol. 183 (7) :4493-4501 (2009)

• Background Reference 04:

  Chang, B.Y., et al. J. Immunol. 183 (3) :2183-2192 (2009)

• Other Product Names:

  Tyrosine-protein kinase JAK3, Janus kinase 3, JAK-3, Jak3

• Tested Applications:

  WB

• Physical Properties:

  Liquid