JAK2 (phospho Tyr1007) Antibody

• Background:

  Plays a role in leptin signaling and control of body weight

• NCBI Gene ID:

  3717

• Swiss Prot:

  O60674

• Accession Number:

  NP_004963.1

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  JAK2 (Phospho-Tyr1007) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 1007 (K-E-Y (p) -Y-K) derived from Human JAK2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Phospho-Specific, Apoptosis, Cancer

• Purification:

  Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

• Concentration:

  1 mg/mL

• Buffer:

  Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Modification:

  Phospho-Specific

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store antibody at -20˚ C for up to one year.

• Calculated Molecular Weight:

  125 kDa

• Specificity:

  This antibody detects endogenous level of JAK2 only when phosphorylated at tyrosine 1007.

• Applications Notes:

  Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100

• Symbol:

  JAK2

• NCBI Official Name:

  Janus kinase 2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  James C, et al. (2005) Nature. 434 (7037) : 1144-1148. Argetsinger LS, et al. (2004) Mol Cell Biol. 24 (11) : 4955-4967. Ungureanu D, et al. (2002) Mol Cell Biol. 22 (10) : 3316-3326. Xie S, et al. (2001) Oncogene. 20 (43) : 6188-6195.

• Other Product Names:

  JTK10, THCYT3, AFX, AFX1, MLLT7, JAK-2, JAK2, Janus kinase 2, kinase Jak2

• Tested Applications:

  WB, IHC

• Protein ID:

  4826776

• Physical Properties:

  Liquid