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JAK3 Antibody

CAT: 0223-13-272Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-13-272Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease) .
NCBI Gene ID
3718
Swiss Prot
P52333
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 750-850 of human JAK3 (NP_000206.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Apoptosis, Cancer, Cell Cycle, Immunology, Signal Transduction, Transcription
Purification
Affinity purification
Positive Control
U-87MG
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 125kDa
Fragment
IgG
Symbol
Jak3
NCBI Official Name
Janus kinase 3
NCBI Organism
Homo sapiens
Other Product Names
JAK-3_HUMAN, JAKL, L-JAK, LJAK, JAK3, tyrosine-protein kinase JAK3, Janus kinase 3 (a protein tyrosine kinase, leukocyte), leukocyte Janus kinase
Tested Applications
WB, IF
Physical Properties
Liquid

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