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C1QC Antibody

CAT: 0223-56-126Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-56-126Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a major constituent of the human complement subcomponent C1q. C1q associates with C1r and C1s in order to yield the first component of the serum complement system. A deficiency in C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N-terminus, and a C-terminal globular region. The A-, B-, and C-chains are arranged in the order A-C-B on chromosome 1. This gene encodes the C-chain polypeptide of human complement subcomponent C1q. Alternatively spliced transcript variants that encode the same protein have been found for this gene.
NCBI Gene ID
714
Swiss Prot
P02747
Accession Number
P02747
Host
Rabbit
Reactivity
Human
Immunogen
This C1QC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 93-120 amino acids from the Central region of human C1QC.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology, Neuroscience
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
26 kDa
Fragment
Rabbit Ig
Symbol
C1QC
NCBI Official Name
Complement C1q subcomponent subunit C
NCBI Organism
Homo sapiens
Background Reference 01
Fraser, D.A., et al. J. Immunol. 185 (7) :3932-3939 (2010)
Background Reference 02
Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)
Background Reference 03
Rafiq, S., et al. Clin. Exp. Immunol. 161 (2) :284-289 (2010)
Background Reference 04
Han, S., et al. Hum. Immunol. 71 (7) :727-730 (2010)
Other Product Names
Complement C1q subcomponent subunit C, C1QC, C1QG
Tested Applications
WB, IHC-P, IF, Flow
Protein ID
20178281
Physical Properties
Liquid

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